Neurotoxicity of Drug Abuse

It is considered as a major cause of neurodegenerative disorders. Most drugs of abuse have essential neurotoxic effects many of which are primarily mediated by several dopaminergic and glutamatergic neurotransmitter systems. Although many researchers have checked the medical and mental conditions on drug abuse, the neurotoxicity induced by these drugs still requires comprehensive attention. The science of neurotoxicity promises to improve therapeutic and preventive strategies for brain disorders such as Alzheimer disease and Parkinson's disease.