In Alzheimer's malady, cerebrum cells begin to break down. The body endeavors to stop this procedure by creating a protein called amyloid. In any case, amyloid stores develop in the cerebrum, prompting further crumbling. These stores of amyloid are alluded to as "plaques" and make the cerebrum cells shrink up and frame "tangles", which thus prompt changes in the mind structure and make the mind cells kick the bucket. The arrangement of plaques and tangles likewise keeps the creation of some essential cerebrum chemicals, called neurotransmitters (eg: acetylcholine, which is imperative in memory work). After some time the loss of cerebrum cells makes the mind recoil.

• Distrust in others
• Irritability and forcefulness
• Changes in resting propensities
• Loss of restraints
• Delusions, for example, thinking something has been stolen